CBE 515 – Chemical Product Design Elective Course

Spring 2021

This course teaches the basics of product design for modern chemical products being designed throughout the chemical, biochemical, pharmaceutical, cosmetics, electronics, agrochemicals, foods, and similar industries – using some of the latest software for chemical product design.  It focuses on innovation; taking new technologies from R&D and creating new products to satisfy the needs of consumers.  What products might evolve from your research?

Lecture: MWF 11:00 a.m.
Recitation: M 4:00 p.m.
No Classes: 2/12, Spring Break – 3/10, 4/12
Instructor: Prof. Warren D. Seider, Rm. 372 TB, 215-898-7953, seider@seas.upenn.edu
Text: Seider, W.D., D.R., Lewin, J.D. Seader, S. Widagdo, R. Gani, K.M. Ng, Product and Process Design Principles, 4th Ed., VitalSource  E-book, Wiley, 2017.


  1. Introduction to Product Design
  2. Molecule and Molecular Mixture Design– ICAS (ProPred and ProCAMD)
  3. Chemical Devices
  4. Lab-on-a-Chip Design – High-Throughput Screening-Kinase Inhibitor
  5. Home Hemodialysis Device
  6. Thin Glass Substrates for LCDs
  7. Functional Product Design – Herbicide Distribution
  8. Formulated Product Design – Sunscreen Design
  9. Batch Process Design and Simulation – Pharmaceutical Products – SUPERPRO DESIGNER
  10. Six-Sigma Product Design
  11. Business Decision Making
  12. Design Optimization
  13. Optimal Design and Scheduling of Batch Processes

Exam: 1 hour at end of semester

Homework: Graded homework assignments to illustrate concepts

Term Project: Each student will carry out a small term project.  It does not involve carrying out a product design project.  Instead, it emphasizes how a new product has evolved and its likely future directions.  Possible products include growth of Si crystals for chips; conversion of CO2 (decarbonization) to high-value chemical products (e.g., omega-3 fatty acids); plastics upcycling to high-value proteins; hemp to nutraceuticals; waste foods to biogas and electricity)

Intended For: Graduate students (first year especially), CBE juniors and seniors

Taught Initially: Spring 2020;  Spring 2021


  1. Cussler, E. L., and G. D. Moggridge, Chemical Product Design, Second Edition, Cambridge University Press, 2011.
  2. Wei, J., Product Engineering: Molecular Structure and Properties, Oxford University Press, 2007.
  3. Ng, K. M., R. Gani, and K. Dam-Johansen (Eds.), Chemical Product Design: Towards a Perspective Through Case Studies, Computer-Aided Chemical Engineering, 23, Elsevier, 2007.
  4. Pissano, G. P., The Development Factory: Lessons from Pharmaceuticals and Biotechnology, Harvard Business School Press, 1997.
  5. Ulrich, K. T., and S. D. Eppinger, Product Design and Development, Second Edition, McGraw-Hill, 2000.
  6. Gundling, E., The 3M Way to Innovation: Balancing People and Profit, Kodansha International, New York, 2000.
  7. Coe, J. T., Unlikely Victory: How General Electric Succeeded in the Chemical Industry, AIChE, 2000.
  8. Cagan, J., and C. M. Vogel, Creating Breakthrough Products: Innovation from Product Planning to Program Approval, Prentice-Hall PTR, 2002.
  9. Gladwell, M., The Tipping Point: How Little Things Can Make a Big Difference, Little, Brown, and Co., New York, 2002.